Malignant peritoneal mesothelioma
is an extremely rare condition. Only 100 to 500 cases are diagnosed in the US
each year, making up less than 30% of all mesothelioma cases.
Peritoneal mesothelioma is a cancer affecting the abdominal lining, or peritoneum (paira-tin-e-um), which is why is is sometimes referrered to as abdominal mesothelioma. This membrane supports and covers the organs of the abdomen.
The peritoneum is made of two parts, the visceral and parietal peritoneum. The visceral peritoneum covers the internal organs and makes up most of the outer layer of the intestinal tract. Covering the abdominal cavity is the parietal peritoneum.
Cells in these linings secrete a fluid which allows organs to move against one another. For instance, as the intestines move food through the body. The cells of the mesothelium are designed to create fluid, but the cancer causes them to overproduce, creating a build up of excess fluid in the abdominal cavity.
Because pleural mesothelioma is more common and often spreads to the peritoneal cavity, it is important to determine if pleural mesothelioma is the primary cancer.
Although there's no definitive explanation, it is widely believed that asbestos causes peritoneal mesothelioma in one of two ways. First, asbestos fibers may be ingested, and when in the intestinal tract, the fibers may work themselves into the peritoneal cavity and peritoneum. Second, they may be inhaled and transported through the lymph node system to the peritoneal cavity.
Malignant
mesothelioma (pronounced "mez-o-theel-e-oh-ma"), also known
as "asbestos cancer," is a rare form of cancer found
in the lining of the chest, lungs, or abdomen. This lining is called the mesothelium
and is where mesothelioma gets its name.
Because tumors of the mesothelium are rarely benign (noncancerous), malignant (cancerous) mesothelioma is usually referred to as simply the shortened "mesothelioma" or, in casual terms, simply "meso."
The mesothelium covers various organs in the body protecting them and allowing organs to move against each other as the lungs expand and contract or the heart beats. The mesothelium surrounding the lungs and lining the chest cavity is called the pleura, so mesothelioma affecting the cells lining the sacs surrounding the chest or lungs is referred to as pleural mesothelioma. When the cancer affects the abdominal lining, or peritoneum, that is peritoneal mesothelioma.